Gene information
Official symbol VDAC1
Official full name voltage dependent anion channel 1
Gene type protein-coding gene
Chromosome5q31.1
Alias symbolMGC111064; PORIN
Gene familyVoltage dependent anion channels
Resources
Entrez Gene 7416
HGNC HGNC:12669
Ensembl ENSG00000213585
Vega OTTHUMG00000129118
UCSC uc003kyr.3
GO terms: 42 records
GO Description Category LogP Number of genes Detail
GO:0005216 ion channel activity GO Molecular Functions -2.12987867 14 More
GO:0005244 voltage-gated ion channel activity GO Molecular Functions -1.48636532 7 More
GO:0005253 anion channel activity GO Molecular Functions -1.99792626 5 More
GO:0005543 phospholipid binding GO Molecular Functions -6.61792344 45 More
GO:0006090 pyruvate metabolic process GO Biological Processes -1.40125944 6 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010506 regulation of autophagy GO Biological Processes -5.54010569 34 More
GO:0010508 positive regulation of autophagy GO Biological Processes -4.14985165 17 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0010821 regulation of mitochondrion organization GO Biological Processes -7.09757912 23 More
GO:0010959 regulation of metal ion transport GO Biological Processes -23.6318171 71 More
GO:0015103 inorganic anion transmembrane transporter activity GO Molecular Functions -2.09965422 7 More
GO:0015267 channel activity GO Molecular Functions -2.12225487 15 More
GO:0015318 inorganic molecular entity transmembrane transporter activity GO Molecular Functions -2.11605072 20 More
GO:0015485 cholesterol binding GO Molecular Functions -6.09984616 12 More
GO:0015698 inorganic anion transport GO Biological Processes -1.84892626 7 More
GO:0016239 positive regulation of macroautophagy GO Biological Processes -4.30642477 12 More
GO:0016241 regulation of macroautophagy GO Biological Processes -3.91265693 18 More
GO:0019900 kinase binding GO Molecular Functions -6.03057706 62 More
GO:0019901 protein kinase binding GO Molecular Functions -6.66055444 59 More
GO:0022803 passive transmembrane transporter activity GO Molecular Functions -2.11455525 15 More
GO:0022832 voltage-gated channel activity GO Molecular Functions -1.48636532 7 More
GO:0022836 gated channel activity GO Molecular Functions -2.68852033 13 More
GO:0030855 epithelial cell differentiation GO Biological Processes -14.2408795 69 More
GO:0032934 sterol binding GO Molecular Functions -5.20663428 12 More
GO:0033218 amide binding GO Molecular Functions -9.50305686 47 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034763 negative regulation of transmembrane transport GO Biological Processes -22.14661 42 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043271 negative regulation of ion transport GO Biological Processes -19.3914052 40 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051924 regulation of calcium ion transport GO Biological Processes -18.2498286 49 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0098656 anion transmembrane transport GO Biological Processes -1.61106579 8 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:1903146 regulation of autophagy of mitochondrion GO Biological Processes -3.18614571 7 More
GO:1903169 regulation of calcium ion transmembrane transport GO Biological Processes -8.80532519 28 More
GO:1903599 positive regulation of autophagy of mitochondrion GO Biological Processes -3.06676630 3 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04020 Calcium signaling pathway KEGG Pathway -10.4415222 36 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
olesoxime TdgClinicalTrial view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
Chr5:134053541 hypomethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
All rights reserved: Soochow University Center for Systems Biology